CJC-1295 and Ipamorelin are two of the most widely studied growth hormone secretagogues in peptide research. When combined, they are investigated for their complementary mechanisms of action on the hypothalamic-pituitary axis. This guide covers what researchers need to know about both compounds and how they are used in laboratory settings.
What is CJC-1295?
CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH), consisting of a modified 29-amino acid sequence. The modification includes a Drug Affinity Complex (DAC) technology that extends the half-life of the compound by binding to albumin in the bloodstream. This results in a prolonged elevation of growth hormone-releasing activity compared to native GHRH.
In research settings, CJC-1295 is studied for its ability to stimulate pulsatile growth hormone secretion from the anterior pituitary gland. Laboratory investigations have examined its effects on GH pulse amplitude, IGF-1 levels, and downstream signaling pathways.
What is Ipamorelin?
Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It belongs to the growth hormone releasing peptide (GHRP) class of compounds and is noted in research for its high selectivity — it stimulates GH release without significantly elevating cortisol or prolactin levels, which distinguishes it from earlier GHRPs like GHRP-2 and GHRP-6.
Ipamorelin acts on the ghrelin receptor (GHS-R1a) through a separate pathway from CJC-1295, making the two compounds a subject of interest for researchers studying synergistic GH secretagogue activity.
Why Are They Studied Together?
The CJC-1295 and Ipamorelin combination is frequently investigated in research because the two compounds act through distinct but complementary mechanisms. CJC-1295 stimulates GHRH receptors while Ipamorelin activates ghrelin receptors — together they are studied for producing a stronger and more sustained GH pulse than either compound alone.
Research into this combination has examined receptor binding kinetics, GH pulse frequency and amplitude, and interactions with the somatostatin feedback system.
Product Specifications
Alpha Tides PNW supplies CJC-1295 + Ipamorelin as a pre-blended lyophilized powder in 20mg vials. Each batch is independently tested by a third-party laboratory with Certificate of Analysis available upon request.
- Form: Lyophilized powder
- Size: 20mg per vial
- Purity: 99%+ verified
- Storage: -20°C, away from light and moisture
Research Use Only
CJC-1295 + Ipamorelin supplied by Alpha Tides PNW is intended strictly for laboratory and in vitro research purposes. It is not for human or animal consumption and has not been evaluated or approved by the FDA.