MOTS-C 10mg

MOTS-C is studied in research involving mitochondrial function, cellular energy, and metabolism. Researchers investigate how mitochondrial signaling may influence the way cells manage and respond to energy.

Technical Research Details

MOTS-C is a mitochondrial-derived peptide that has become a subject of laboratory research involving mitochondrial signaling, cellular metabolism, adaptive stress responses, and communication between mitochondrial and nuclear pathways.

This product is supplied exclusively as a research material. It is not intended for diagnostic, therapeutic, dietary, cosmetic, veterinary, or human use.
Product Information

Product: MOTS-C
Form: Lyophilized powder
SKU: AT-MOTS-C
Storage: Keep dry and away from direct light before reconstitution. Refrigerate after reconstitution.
Use: For laboratory research use only. Not for human or animal use.

Purity
99.39%
Research Notes
MOTS-C is a short peptide encoded within the mitochondrial genome rather than the nuclear genome, distinguishing it from many other research peptides. It was first characterized as part of a small class of "mitochondrial-derived peptides," and its discovery is frequently cited as evidence that mitochondrial DNA encodes signaling molecules beyond its traditionally recognized role in oxidative phosphorylation.

Research interest in MOTS-C centers on its proposed role as a messenger between mitochondria and the cell nucleus — a concept researchers refer to as mitochondrial-nuclear retrograde signaling. Preclinical literature has examined its interaction with cellular energy-sensing pathways, including AMPK signaling and folate-cycle-related metabolic processes, in the context of how cells respond to metabolic stress.

Because this research area is still developing relative to more extensively characterized peptides, researchers should treat mechanistic findings as an active and evolving area of study rather than settled conclusions.
Documentation
Supplier-provided laboratory documentation is available for this product. This report was not independently commissioned by Alpha Tides PNW — see our Certificates of Analysis page for the full document and source notes.
Frequently Asked Questions
What is MOTS-C used for in research?
MOTS-C is primarily used in laboratory research examining mitochondrial-nuclear signaling, cellular energy sensing, and mitochondrial-derived peptide biology. It is supplied strictly as a research material for qualified laboratory use.
What makes MOTS-C different from other research peptides?
Unlike most research peptides, MOTS-C is encoded by mitochondrial rather than nuclear DNA. This distinguishes its research applications, which focus on mitochondrial signaling biology rather than the receptor-binding pathways studied with many other compounds.
Where can I find related research guides?
The Alpha Tides Research Hub contains guides on storage, reconstitution, and compound profiles for the full research catalog.
Research Use Disclaimer
This product is intended strictly for laboratory research use only. It is not a drug, food, or cosmetic and is not intended for human or animal consumption. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease or condition.