PT-141 10mg

PT-141 is a research peptide studied for pathways involved in sexual arousal and sexual-response signaling. Researchers investigate how melanocortin signaling in the brain influences these biological responses. Alpha Tides supplies PT-141 as a 10mg lyophilized powder for laboratory research use.

Technical Research Details

PT-141 (Bremelanotide) is a synthetic cyclic peptide derived from Melanotan II. It has been referenced in laboratory research examining peptide structure, molecular interactions, receptor-related mechanisms, and biochemical signaling pathways. Its molecular characteristics make it a subject of interest in analytical and experimental research. Alpha Tides supplies PT-141 as a 10mg lyophilized powder for laboratory research use.
Product Information

Form: Lyophilized powder
Contents: 10mg per vial
Structure: Cyclic heptapeptide derived from MT-II
Primary receptor targets: MC3R, MC4R (CNS-selective profile)
Storage: −20°C lyophilized; 2–8°C after reconstitution
Use: For laboratory and in vitro research use only

Research Applications

Melanocortin receptor pharmacology: MC3R/MC4R binding affinity studies and downstream cAMP signaling characterization
CNS signaling research: Hypothalamic and limbic system melanocortin pathway studies
Neuroendocrine research: Hypothalamic-pituitary axis interactions and hormonal signaling downstream of MC4R activation
Receptor selectivity studies: Comparative pharmacological research between PT-141 and MT-II to examine structural modification effects on receptor selectivity
Behavioral neuroscience: Animal model research examining MC3R/MC4R involvement in reward and motivated behaviors
Autonomic nervous system studies: Downstream autonomic regulation mediated via hypothalamic melanocortin receptor activation

Research Notes
PT-141 is a synthetic cyclic peptide structurally related to Melanotan II (MT-II). Its molecular structure and chemical characteristics have made it a subject of laboratory research examining peptide properties, molecular interactions, and receptor-related mechanisms.

Research involving PT-141 and related compounds includes the study of molecular structure, receptor interactions, and biochemical signaling processes in controlled laboratory settings. Its documented structural and molecular characteristics make it a reference compound for analytical and experimental research.
Frequently Asked Questions
What is PT-141 used for in research?
PT-141 is used to study MC3R and MC4R receptor pharmacology in CNS-mediated signaling, neuroendocrine regulation, and autonomic function research. It is also used in comparative pharmacology studies examining receptor selectivity differences between PT-141 and its structural precursor, MT-II.
How does PT-141 differ from MT-II?
PT-141 was derived from MT-II via structural modification to reduce MC1R pigmentation activity while retaining MC3R/MC4R affinity. MT-II is a non-selective agonist across MC1R through MC5R; PT-141 has a more CNS-selective receptor engagement profile, making the two useful for comparative mechanistic studies.
How should PT-141 be stored?
Store lyophilized vials at −20°C before reconstitution. After reconstitution with bacteriostatic water, refrigerate at 2–8°C and use within 14 days.
Research Use Disclaimer
This product is intended strictly for laboratory research use only. It is not a drug, food, or cosmetic and is not intended for human or animal consumption. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease or condition.