PT-141 10MG

Description

What is PT-141?

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide derived from Melanotan II. It acts as a non-selective agonist at melanocortin receptors, with particular affinity for MC3R and MC4R subtypes located in the central nervous system. Unlike peripherally-acting compounds, PT-141 operates via CNS pathways, making it a distinct subject of interest in neuropharmacology research.

Research into melanocortin receptor signaling has expanded significantly, with PT-141 serving as a key investigative tool for understanding the role of these receptors in neuroendocrine and autonomic function.

Research Areas

PT-141 has been investigated across several areas of preclinical and clinical neuropharmacological research:

Melanocortin Receptor Pharmacology – This compound binds selectively to MC3R and MC4R receptors in the hypothalamus and limbic system. Research has examined how activation of these receptors modulates downstream signaling cascades involved in autonomic nervous system regulation.

Central Nervous System Signaling – Studies have investigated PT-141’s role in hypothalamic neural circuits, particularly those involved in neuroendocrine communication and homeostatic regulation. Research models have used Bremelanotide to probe the relationship between melanocortin tone and CNS output.

Neuroendocrine Research – This compound has been used in preclinical models to study interactions between the melanocortin system and the hypothalamic-pituitary axis. Researchers have examined how MC4R activation influences hormonal signaling pathways.

Receptor Selectivity Studies – Comparative research between Bremelanotide and its precursor Melanotan II has investigated the functional significance of structural modifications on receptor binding profiles and downstream pharmacological activity.

Behavioral Neuroscience – Animal model research has explored the role of melanocortin receptor activation in motivated and reward-related behaviors, using PT-141 as a pharmacological probe for MC3R/MC4R involvement.

Storage & Handling

PT-141 should be stored lyophilized at -20°C and protected from light. Once reconstituted, store at 4°C and use within 14 days. Avoid repeated freeze-thaw cycles. Reconstitute with sterile bacteriostatic water only. Handle under sterile laboratory conditions.

This product is intended for research use only. Not for human consumption. Not for veterinary use. For laboratory and in vitro research purposes only.