NAD+1000

Description

Buy NAD+ 1000mg (Nicotinamide Adenine Dinucleotide) — research-grade lyophilized coenzyme available exclusively for laboratory and scientific research purposes.

What Is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell and one of the most actively researched molecules in modern longevity and metabolic biology. NAD+ functions as a critical electron carrier in redox reactions and serves as a substrate for key enzymes including sirtuins, PARPs, and CD38 — all of which are linked to DNA repair, gene expression regulation, and cellular stress response.

Research indicates that NAD+ levels decline by approximately 50% between ages 40 and 60, driven by increased CD38 activity, chronic inflammation, and reduced biosynthesis. This age-related decline has made NAD+ a primary focus of studies examining metabolic health, mitochondrial function, cognitive performance, and cellular energy production.

Research Areas

NAD+ has been the subject of extensive preclinical and clinical research across multiple biological systems:

Cellular Energy Metabolism — NAD+ plays a central role in the mitochondrial electron transport chain, directly supporting ATP production. Preclinical studies have examined how restoring NAD+ levels influences mitochondrial efficiency and overall cellular energy output in aged tissue models.

Sirtuin Activation — Sirtuins (SIRT1–SIRT7) are NAD+-dependent enzymes that regulate gene expression, inflammation, and metabolic homeostasis. Research has investigated how NAD+ availability influences sirtuin activity and downstream effects on cellular aging pathways.

DNA Repair via PARP Activation — PARP enzymes consume NAD+ during DNA damage repair. Studies have examined the relationship between NAD+ availability and PARP-mediated repair efficiency, particularly in models of oxidative stress and genomic instability.

Mitochondrial Function — Research has explored NAD+’s role in maintaining mitochondrial membrane potential, biogenesis, and function. Preclinical models have shown that NAD+ repletion may support mitochondrial health in aging and metabolic dysfunction models.

Redox Signaling — As a key electron carrier cycling between NAD+ and NADH, this coenzyme is central to cellular redox balance. Studies have examined its role in regulating oxidative stress responses across multiple tissue types.

Injectable vs. Oral Precursors — Research comparing injectable NAD+ to oral precursor compounds such as NMN and NR has shown that injectable NAD+ produces more direct and immediate tissue-level increases compared to precursors that require multiple enzymatic conversion steps.

Cognitive and Neuroprotective Research — Animal studies have examined NAD+’s potential neuroprotective properties, with researchers investigating its role in supporting neuronal energy metabolism and resilience against age-related cognitive decline.

Product Specifications

• Compound: Nicotinamide Adenine Dinucleotide (NAD+)
• CAS Number: 53-84-9
• Size: 1000mg lyophilized powder
• Purity: ≥99% (HPLC verified)
• Appearance: White lyophilized powder
• Reconstitution: Requires bacteriostatic water (BAC water) prior to use
• Storage: Store at -20°C, sealed, protected from heat and light
• Format: Single amber glass vial

Why Source NAD+ From Alpha Tides?

At Alpha Tides, every compound in our catalog is sourced from verified manufacturers and held to strict purity standards. We supply researchers with laboratory-grade peptides and coenzymes backed by Certificates of Analysis (COA) available upon request. Our focus is reliability, consistency, and discreet domestic shipping — so your research program stays on schedule.

Alpha Tides supplies NAD+ 1000mg to researchers seeking consistent, high-purity research compounds with reliable domestic shipping from the Pacific Northwest.

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This product is intended strictly for research use only (RUO). Not for human consumption, veterinary use, or household use. For use by qualified researchers in controlled laboratory settings only. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease or condition.